Brian L. Wickes, Ph.D.

P1010368

RESEARCH

Dr. Brian L. Wickes laboratory is interested in the molecular biology of differentiation in Cryptococcus neoformans and the identification and diagnosis of medically important fungi. This interest is manifested in a number of different projects that range from basic research to translational clinical studies and in some areas, extends beyond fungi into bacteria. 

Selected Publications

Farmer AR, Murray CK, Driscoll IR, Wickes BL, Wiederhold N, Sutton DA, Sanders C, Mende K, Enniss B, Feig J, Ganesan A, Rini EA, Vento TJ. Combat-Related Pythium aphanidermatum Invasive Wound Infection: Case Report and Discussion of Utility of Molecular Diagnostics. J Clin Microbiol. 2015 Jun;53(6):1968-75.

Wiederhold NP, Najvar LK, Matsumoto S, Bocanegra RA, Herrera ML, Wickes BL, Kirkpatrick WR, Patterson TF. Efficacy of the Investigational Echinocandin ASP9726 in a Guinea Pig Model of Invasive Pulmonary Aspergillosis. Antimicrob Agents Chemother. 2015 May;59(5):2875-81.

Romanelli AM, Fu J, Herrera ML, Wickes BLA universal DNA extraction and PCR amplification method for fungal rDNA sequence-based identification. Mycoses. 2014 Oct;57(10):612-22.

De Ravin SS, Parta M, Sutton DA, Wickes BL, Thompson EH, Wiederhold NP, Nakasone KK, Alimchandani M, OConnell A, Notarangelo L, Kang E, Malech HL, Zelazny AM. Paravertebral mushroom: identification of a novel species of Phellinus as a human pathogen in chronic granulomatous disease. J Clin Microbiol. 2014 Jul;52(7):2726-9.

Kozel TR, Wickes BFungal diagnostics. Cold Spring Harb Perspect Med. 2014 Apr 1;4(4):a019299.

Cheng Z, Zhou T, Merchant A, Prihoda TJ, Wickes BL, Xu G, Walter CA, Rebel VI. Identifying DNA mutations in purified hematopoietic stem/progenitor cells. J Vis Exp. 2014 Feb 24;(84):e50752. doi: 10.3791/50752. PubMed PMID: 24637843.

Wiederhold NP, Sutton DA, Li DW, Liang Y, Thompson EH, Wickes BL, Herrera ML, Rhoads SL, Mortensen JE. Stachybotrys eucylindrospora isolated from foreign material following a traumatic eye injury. Mycoses. 2014 Jul;57(7):437-41.

Burnham CA, Frobel RA, Herrera ML, Wickes BLRapid ertapenem susceptibility testing and Klebsiella pneumoniae carbapenemase phenotype detection in Klebsiella pneumoniae isolates by use of automated microscopy of immobilized live bacterial cells. J Clin Microbiol. 2014 Mar;52(3):982-6.

Cardile AP, Briggs H, Burguete SR, Herrera M, Wickes BL, Jorgensen JH. Treatment of KPC-2 Enterobacter cloacae empyema with cefepime and levofloxacin. Diagn Microbiol Infect Dis. 2014 Feb;78(2):199-200.

Simon MS, Somersan S, Singh HK, Hartman B, Wickes BL, Jenkins SG, Walsh TJ, Schuetz AN. Endocarditis caused by Rhodotorula infection. J Clin Microbiol. 2014 Jan;52(1):374-8.

Cardile AP, Briggs H, Burguete SR, Herrera M, Wickes BL, Jorgensen JH. Treatment of KPC-2 Enterobacter cloacae empyema with cefepime and levofloxacin. Diagn Microbiol Infect Dis. 2014 Feb;78(2):199-200.

Wiederhold NP, Sutton DA, Li DW, Liang Y, Thompson EH, Wickes BL, Herrera ML, Rhoads SL, Mortensen JE. Stachybotrys eucylindrospora isolated from foreign material following a traumatic eye injury. Mycoses. 2014 Jan 22.

Fu J, Morris IR, Wickes BL. The production of monokaryotic hyphae by Cryptococcus neoformans can be induced by high temperature arrest of the cell cycle and is independent of same-sex mating. PLoS Pathog. 2013;9(5):e1003335. 

Lyon GM, Abdul-Ali D, Loeffler J, White PL, Wickes B, Herrera ML, Alexander BD, Baden LR, Clancy C, Denning D, Nguyen MH, Sugrue M, Wheat LJ, Wingard JR, Donnelly JP, Barnes R, Patterson TF, Caliendo AM; AsTeC, IAAM, EAPCRI Investigators. Development and evaluation of a calibrator material for nucleic acid-based assays for diagnosing aspergillosis. J Clin Microbiol. 2013 Jul;51(7):2403-5.

Professor
Microbiology, Immunology, and Molecular Genetics 

Education

Ph.D., Microbiology, Catholic University, 1992

M.S., Microbiology, Catholic University, 1984

B.S., Biology, Catholic University, 1980

Contact

Email: WICKES@UTHSCSA.EDU

Phone: (210) 567-3938

Research Profile
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