The long-term goal of Dr. Nu Zhang's research is to understand the biology and function of tissue-resident memory T
(Trm) cells and tumor infiltrating T cells in health and disease, and the role
of Transforming Growth Factor-b (TGF-b) in
their differentiation, homeostasis and metabolic regulation.
Nu Zhang and Michael J. Bevan. Transforming growth factor-b signaling controls the formation
and maintenance of gut-resident memory T cells by regulating migration and
Immunity, 2013 Oct
17;39 (4):687-96. doi: 10.1016/j.immuni.2013.08.019.
Nu Zhang and Michael J. Bevan. TGF-b signaling to T cells inhibits autoimmunity during lymphopenia-driven proliferation.
Nat Immunol. 2012 May 27; 13(7): 667-73. doi: 10.1038/ni.2319.
Nu Zhang and Michael J. Bevan. CD8+ T cells: foot soldiers of the immune system.
2011 Aug; 35 (2): 161-168.
Nu Zhang and Michael J. Bevan. Dicer Controls CD8 + T cell Activation, Migration and Survival. PNAS. 2010 107 (50): 21629-21634.
Nu Zhang and You-Wen He. An essential role c-FLIP in the efficient development of mature T lymphocytes.
J Exp. Med.
2005 Aug 1; 202(3):395-404. Epub 2005 Jul 25.